GABA (Gamma-Amino Butyric Acid) Information
GABA (Gamma-Amino Butyric Acid)
GABA is a major inhibitory neurotransmitter in the central nervous system. When
the level of GABA in the brain decreases below a certain level, seizures and other
neurological disorders may occur. The level of GABA in the brain is controlled by
two enzymes, glutamate decarboxylase (GAD) and GABA transaminase (GABA-T).
GABA is considered to act as a natural calming and anti-epileptic agent in the
brain. Since GABA is not transported efficiently into the brain from the bloodstream,
most of the GABA found in the brain is manufactured there. For that reason, supplemental
GABA would not be expected to increase levels of GABA in the brain. Howver, a few
physicians have reported that GABA can be beneficial when used in connection with
a variety of brain disorders including epilepsy and schizophrenia, but these reports
have not been substantiated by human pharmacological studies. Intake of high levels
GABA has shown to produce a marked increase in plasma growth-hormone levels and
prolactin in one study, but the implication and application of these findings is
not yet clear.
Usage and Dosage
GABA can be purchased as a nutritional supplement in capsule and tablet form.
Some doctors have recommended GABA in the amount of 200 mg four times daily, although
no general recommendation is made for supplementation of GABA.
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you might have a health problem.
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